‘Nitroglycerin’

Research the use of Nitroglycerin for Cancer

Wednesday, March 31st, 2010

“The Treatment of prostate cancer with a very low dose of nitroglycerin can slow or even stop the progression of the disease without serious side effects of current treatments. At least that is confirmed by researchers from Queen’s University responsible for this new research, which I personally left me impressed.

The findings are the result of the first clinical trial using nitroglycerin to treat prostate cancer. The 24-month Phase II study has been directed to 29 men with high levels of prostate specific antigen (PSA, a key indicator of the progression of cancer) after prostate surgery or radiation. “We are very excited to see a significant slowdown in disease progression as evidenced by PSA levels, and to see this outcome in many of the men who participated in the study,” says Robert Siemens, the study leader Professor of Urology at Queen’s University at Kingston General Hospital urologist.

Researchers are encouraged by the results, especially because at present the safe and effective treatments for men with rising PSA levels after surgery or radiation are limited. They note further that the additional evidence is needed to confirm the results of this study are very small.

Of the 17 patients who completed the study, all but one showed a stabilization or decrease in the rate of cancer progression, as measured by PSA doubling time. Nitroglycerin has already been used significantly higher doses for over a century in the treatment of angina pectoris, has proven without a doubt his power to reduce nitric oxide, which plays an important role in the progression of a tumor. (more…)

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