‘EGFR gene mutation’

Discovery of a Subtype of Lung Cancer can Improve Treatment

Monday, August 16th, 2010

The Spanish Group of Lung Cancer (GECP) has discovered a new subtype of lung cancer that responds best to the application of a particular drug that traditional chemotherapy.

This has been explained to this group, consisting of 266 Spanish oncologists who have undergone study of more than 2,100 patients with lung cancer. The investigation shows that people who had EGFR gene mutation, and were treated with a specific drug, obtained a higher response rate.

This is the first large European study, which was published in The New England Journal of Medicine “and has performed in the laboratory of Molecular Biology Universiatario ICO-Hospital Germans Trias i Pujol in Badalona.

“The median survival for patients receiving the drug ‘erlotinib’ was between 14 and 27 months, almost a year longer than with traditional chemotherapy,” stated the GECP.

The gene called Factor Receptor (EGFR) is found naturally on the cell surface and its mutation occurs when there excessive activity, which can lead to uncontrolled cell division and increased predisposition to cancer.

(more…)

Tags: , , ,
Posted in Cancer Risk Factors | 1 Comment »