How the Relationship Between Cancer with Stress

Posted by | March 21st, 2010 in Brain cancer | No Comments »

China and the first U.S. scientific research shows that there is a direct relationship between cancer and stress.

Studies show edition was published in the journal Nature, the scientists say where the victim cell stress signals that promote tumor that affects the generation of healthy cells around it.
The study was conducted on fruit flies, but studies show that the same genes and the same biological sequences involved in this process present in humans.

So far, it is known that chronic inflammation, the main cause of stress, associated with tumor growth in cancer patients and some experts argue that the negative emotions, stress hormones, inflammation and cancer may be related to each other, although there is no clear evidence.

There is also a consensus that cancer-causing genetic mutation affecting only individual cells, but these studies show that this does not always happen, as various mutations in different cells can collaborate with each other in the generation and development of tumors.

Study authors focused their work on the activity of two mutant genes cause cancer.

One is the RAS, which is associated with 30 percent of cases of this disease, and the other is a tumor suppressor gene, known as a “doodle”, which when present in leading the development of cancer defects.

However, even a mutated RAS gene or a mutant version of “doodle” it can cause cancer.

The researchers studied fruit flies that carry both gene mutation and found that a cell with only mutant RAS can lead to malignancy if it involves a nearby cell with a “doodle” damaged.

The conclusion is that stress is a factor that unites the two cells, a protein marker, called cicotinas order to move from cell to cell.

Professor Tian Xu of the University of Connecticut School of Medicine (U.S.), head of research, said “bad news” because “there are many conditions that can trigger physical and emotional stress and infection and inflammation.

In short, studies show that it is easier than to think that cancer is rooted in the human body, noted that the more likely that mutations in some cells ceben that one.

The good news is that it also identifies a potential new way to stop the cancer, if successfully blocked from receiving signals cell stress.

“A better understanding of the mechanisms underlying the generation of cancer has provided new tools to fight disease,” said Professor Wu.


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